In 2020, a new minigame appeared in the video game Borderlands 3 , located in the resident scientists laboratory on the spaceship Sanctuary III . Although the arcade game may seem like just another way to pass in game time, the tile matching puzzle game— Borderlands Science —has allowed millions of players to help map the human gut microbiome. Borderlands Science is one of the first examples of a citizen science game being embedded in a mainstream video game; it translates players tile matchi

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